Recombinant human BLOC1S2 protein
BLOC1S2 (Biogenesis of lysosome-related organelles complex 1 subunit 2) belongs to the BLOC1S2 family. BLOC-1 or biogenesis of lysosome-related organelles complex 1 is a ubiquitously expressed multisubunit protein complex. BLOC-1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. This protein plays a role in cell proliferation. Recombinant human BLOC1S2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Biogenesis of lysosomal organelles complex-1subunit 2, biogenesis of lysosomal organelles complex-1, subunit 2, BLOS2, RP11-316M21.4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
18.5 kDa (166aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Starcevic M., et al. (2004) J. Biol. Chem. 279:28393-28401; ; Wang Z., et al. (2004) J. Mol. Biol. 343:71-82
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 50 mM NaCl
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_776170
Uniprot Accession Number
Q6QNY1
Species
Human
AA Sequence
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