Recombinant human BLOC1S2 protein

BLOC1S2 (Biogenesis of lysosome-related organelles complex 1 subunit 2) belongs to the BLOC1S2 family. BLOC-1 or biogenesis of lysosome-related organelles complex 1 is a ubiquitously expressed multisubunit protein complex. BLOC-1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. This protein plays a role in cell proliferation. Recombinant human BLOC1S2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Biogenesis of lysosomal organelles complex-1subunit 2, biogenesis of lysosomal organelles complex-1, subunit 2, BLOS2, RP11-316M21.4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

18.5 kDa (166aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

BLOC1S2, biogenesis of lysosomal organelles complex-1subunit 2, biogenesis of lysosomal organelles complex-1, subunit 2, BLOS2, RP11-316M21.4, ATGP1528-10 µg, ATGP1528-20 µg, ATGP1528-50 µg, ATGP1528-100 µg, ATGP1528-250 µg, ATGP1528-500 µg, ATGP1528-1 mg, ATGP1528-10, ATGP1528-20, ATGP1528-50, ATGP1528-100, ATGP1528-250, ATGP1528-500, ATGP1528-1

References & Citations

Starcevic M., et al. (2004) J. Biol. Chem. 279:28393-28401; ; Wang Z., et al. (2004) J. Mol. Biol. 343:71-82

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 50 mM NaCl

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_776170

Uniprot Accession Number

Q6QNY1

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAAAAE GVLATRSDEP ARDDAAVETA EEAKEPAEAD ITELCRDMFS KMATYLTGEL TATSEDYKLL ENMNKLTSLK YLEMKDIAIN ISRNLKDLNQ KYAGLQPYLD QINVIEEQVA ALEQAAYKLD AYSKKLEAKY KKLEKR