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Recombinant mouse GRO alpha/CXCL1 protein

CXCL1, also known as GROA or GRO-alpha, is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer. Recombinant mouse CXCL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

C-X-C motif chemokine ligand 1, Growth-regulated alpha protein, Platelet-derived growth factor-inducible protein KC, Secretory protein N51, Fsp, Gro1, KC, KC/GRO-alpha, Mgsa, N51, Scyb1

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

10.5 kDa (97aa) confirmed by MALDI-TOF

Additionnal Information

CXCL1, KC, Chemokine (C-X-C motif) ligand 1, GRO, GRO1, GROA, MGSA, SCYB1, GRO-alpha, ATGP1525-10 µg, ATGP1525-20 µg, ATGP1525-50 µg, ATGP1525-100 µg, ATGP1525-250 µg, ATGP1525-500 µg, ATGP1525-1 mg, ATGP1525-10, ATGP1525-20, ATGP1525-50, ATGP1525-100, ATGP1525-250, ATGP1525-500, ATGP1525-1

References & Citations

Sun, D.. et al. . (2011) Nat. Immunol. 12 (9), 853-860; ; Oka, M., et al. (2011) Lab. Invest. 91 (5), 711-718

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_032202

Uniprot Accession Number

P12850

Species

Mouse

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAPIAN ELRCQCLQTM AGIHLKNIQS LKVLPSGPHC TQTEVIATLK NGREACLDPE APLVQKIVQK MLKGVPK

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