Recombinant human 4-1BB/CD137/TNFRSF9 protein
TNFRSF9, also known as CD137 or ILA, is a member of the TNF superfamily of receptors. This protein is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. TNFRSF9 is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Recombinant human TNFRSF9 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
20 kDa (193aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Langstein J., et al. (2000) Biochem Biophys Res. 273:117-122.; ; Kienzle G., et al. (2000) Int. Immunol. 12: 73-82.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Scientific Category
Immunology
NCBI Accession Number
NP_001552
Uniprot Accession Number
Q07011
Species
Human
AA Sequence
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