Recombinant human 4-1BB/CD137/TNFRSF9 protein

TNFRSF9, also known as CD137 or ILA, is a member of the TNF superfamily of receptors. This protein is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. TNFRSF9 is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Recombinant human TNFRSF9 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

20 kDa (193aa) confirmed by MALDI-TOF

Additionnal Information

41BB, TNFRSF9, Tumor necrosis factor receptor superfamily member 9, Tumor necrosis factor receptor superfamily, member 9, 4-1BB ligand receptor, CD137, CDw137, ILA, ATGP1522-10 µg, ATGP1522-20 µg, ATGP1522-50 µg, ATGP1522-100 µg, ATGP1522-250 µg, ATGP1522-500 µg, ATGP1522-1 mg, ATGP1522-10, ATGP1522-20, ATGP1522-50, ATGP1522-100, ATGP1522-250, ATGP1522-500, ATGP1522-1

References & Citations

Langstein J., et al. (2000) Biochem Biophys Res. 273:117-122.; ; Kienzle G., et al. (2000) Int. Immunol. 12: 73-82.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_001552

Uniprot Accession Number

Q07011

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMFERTRS LQDPCSNCPA GTFCDNNRNQ ICSPCPPNSF SSAGGQRTCD ICRQCKGVFR TRKECSSTSN AECDCTPGFH CLGAGCSMCE QDCKQGQELT KKGCKDCCFG TFNDQKRGIC RPWTNCSLDG KSVLVNGTKE RDVVCGPSPA DLSPGASSVT PPAPAREPGH SPQ