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Recombinant human Glutathione S-transferase omega 2/GSTO2 protein

Glutathione S-transferase omega 2, also known as GSTO2, belongs to the GST superfamily and may be involved in catalyzing the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. GSTO2 is related to GSTO1 and is expressed in a variety of tissues throughout the body where it functions to catalyze the conversion of RX and glutathione to HX and R-S-glutathione. Recombinant human GSTO2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Glutathione S-transferase omega 2, bA127L20.1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

30.6 kDa (266aa) confirmed by MALDI-TOF

Additionnal Information

GSTO2, Glutathione S-transferase omega 2, bA127L20.1, ATGP1515-10 µg, ATGP1515-20 µg, ATGP1515-50 µg, ATGP1515-100 µg, ATGP1515-250 µg, ATGP1515-500 µg, ATGP1515-1 mg, ATGP1515-10, ATGP1515-20, ATGP1515-50, ATGP1515-100, ATGP1515-250, ATGP1515-500, ATGP1515-1

References & Citations

Chariyalertsak S., et al. (2009) Tumori. 95:739-743.; ; Andonova I E., et al. (2010) Treat. 121: 497-52.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 1mM DTT, 40% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_899062

Uniprot Accession Number

Q9H4Y5

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSGDATR TLGKGSQPPG PVPEGLIRIY SMRFCPYSHR TRLVLKAKDI RHEVVNINLR NKPEWYYTKH PFGHIPVLET SQCQLIYESV IACEYLDDAY PGRKLFPYDP YERARQKMLL ELFCKVPHLT KECLVALRCG RECTNLKAAL RQEFSNLEEI LEYQNTTFFG GTCISMIDYL LWPWFERLDV YGILDCVSHT PALRLWISAM KWDPTVCALL MDKSIFQGFL NLYFQNNPNA FDFGLC

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