Recombinant human LAIR2 protein
LAIR2, also known as leukocyte-associated immunoglobulin-like receptor 2, is a secreted, 131 amino acid (aa) protein that contains one IglikeC2 type domain, making it a member of the Ig superfamily. Although one is secreted and one is membranebound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similaradhesion profiles. This suggests that LAIR2 may compete with LAIR1 for ligand binding. Recombinant human LAIR2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Leukocyte-associated immunoglobulin-like receptor, CD306
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
15.2 kDa (139aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Meyaard L., et al. (1997) Immunity. 7:283-290; ; Meyaard L., et al. (1999) J. Immunol. 162:5800-5804
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Scientific Category
Immunology
NCBI Accession Number
NP_067154
Uniprot Accession Number
Q6ISS4
Species
Human
AA Sequence
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