Recombinant human LAIR2 protein

LAIR2, also known as leukocyte-associated immunoglobulin-like receptor 2, is a secreted, 131 amino acid (aa) protein that contains one IglikeC2 type domain, making it a member of the Ig superfamily. Although one is secreted and one is membranebound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similaradhesion profiles. This suggests that LAIR2 may compete with LAIR1 for ligand binding. Recombinant human LAIR2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Leukocyte-associated immunoglobulin-like receptor, CD306

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

15.2 kDa (139aa) confirmed by MALDI-TOF

Additionnal Information

LAIR2, Leukocyte-associated immunoglobulin-like receptor, CD306, ATGP1501-10 µg, ATGP1501-20 µg, ATGP1501-50 µg, ATGP1501-100 µg, ATGP1501-250 µg, ATGP1501-500 µg, ATGP1501-1 mg, ATGP1501-10, ATGP1501-20, ATGP1501-50, ATGP1501-100, ATGP1501-250, ATGP1501-500, ATGP1501-1

References & Citations

Meyaard L., et al. (1997) Immunity. 7:283-290; ; Meyaard L., et al. (1999) J. Immunol. 162:5800-5804

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_067154

Uniprot Accession Number

Q6ISS4

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMQEGAL PRPSISAEPG TVISPGSHVT FMCRGPVGVQ TFRLEREDRA KYKDSYNVFR LGPSESEARF HIDSVSEGNA GLYRCLYYKP PGWSEHSDFL ELLVKGTVPG TEASGFDAP