Recombinant human ADRM1 protein

ADRM1, also known as proteasomal ubiquitin receptor ADRM1, functions as a proteasomal ubiquitin receptor. This protein is an integral plasma membrane protein which promotes cell adhesion. ADRM1 is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Recombinant human ADRM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Proteasomal ubiquitin receptor ADRM1, ARM1, GP110, Rpn13

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

44.7 kDa (431aa) confirmed by MALDI-TOF

Additionnal Information

ADRM1, Proteasomal ubiquitin receptor ADRM1, ARM1, GP110, Rpn13, ATGP1498-10 µg, ATGP1498-20 µg, ATGP1498-50 µg, ATGP1498-100 µg, ATGP1498-250 µg, ATGP1498-500 µg, ATGP1498-1 mg, ATGP1498-10, ATGP1498-20, ATGP1498-50, ATGP1498-100, ATGP1498-250, ATGP1498-500, ATGP1498-1

References & Citations

Hamazaki J., et al. (2006) EMBO J. 25:4524-4536; ; Qiu X.-B., et al. (2006) EMBO J. 25:5742-5753

Other References

Izaguirre-Carbonell J, et al. Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity. (Sci Rep. 2015) {https://www.ncbi.nlm.nih.gov/pubmed/26456697}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_783163

Uniprot Accession Number

Q16186

Species

Human

AA Sequence

MTTSGA LFPSLVPGSR GASNKYLVEF RAGKMSLKGT TVTPDKRKGL VYIQQTDDSL IHFCWKDRTS GNVEDDLIIF PDDCEFKRVP QCPSGRVYVL KFKAGSKRLF FWMQEPKTDQ DEEHCRKVNE YLNNPPMPGA LGASGSSGHE LSALGGEGGL QSLLGNMSHS QLMQLIGPAG LGGLGGLGAL TGPGLASLLG SSGPPGSSSS SSSRSQSAAV TPSSTTSSTR ATPAPSAPAA ASATSPSPAP SSGNGASTAA SPTQPIQLSD LQSILATMNV PAGPAGGQQV DLASVLTPEI MAPILANADV QERLLPYLPS GESLPQTADE IQNTLTSPQF QQALGMFSAA LASGQLGPLM CQFGLPAEAV EAANKGDVEA FAKAMQNNAK PEQKEGDTKD KKDEEEDMSL D