Recombinant human ATOH1 protein
ATOH1, also known as protein atonal homolog 1, activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. This protein may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. Recombinant human ATOH1 protein was expressed in E. coli.
Product Specifications
Product Name Alternative
Protein atonal homolog 1, ATH1, bHLHa14, HATH1, MATH-1
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
21.3 kDa (198aa)
Additionnal Information
References & Citations
Ben-Arie N., et al. (1996) Hum. Mol. Genet. 5:1207-1216; ; The MGC Project Team (2004) Genome Res. 14:2121-2127
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_005163
Uniprot Accession Number
Q92858
Species
Human
AA Sequence
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