Recombinant human ATOH1 protein

ATOH1, also known as protein atonal homolog 1, activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. This protein may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. Recombinant human ATOH1 protein was expressed in E. coli.

Product Specifications

Product Name Alternative

Protein atonal homolog 1, ATH1, bHLHa14, HATH1, MATH-1

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

21.3 kDa (198aa)

Additionnal Information

ATOH1, Protein atonal homolog 1, ATH1, bHLHa14, HATH1, MATH-1, ATGP1485-10 µg, ATGP1485-20 µg, ATGP1485-50 µg, ATGP1485-100 µg, ATGP1485-250 µg, ATGP1485-500 µg, ATGP1485-1 mg, ATGP1485-10, ATGP1485-20, ATGP1485-50, ATGP1485-100, ATGP1485-250, ATGP1485-500, ATGP1485-1

References & Citations

Ben-Arie N., et al. (1996) Hum. Mol. Genet. 5:1207-1216; ; The MGC Project Team (2004) Genome Res. 14:2121-2127

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_005163

Uniprot Accession Number

Q92858

Species

Human

AA Sequence

MKQRRLAANA RERRRMHGLN HAFDQLRNVI PSFNNDKKLS KYETLQMAQI YINALSELLQ TPSGGEQPPP PPASCKSDHH HLRTAASYEG GAGNATAAGA QQASGGSQRP TPPGSCRTRF SAPASAGGYS VQLDALHFST FEDSALTAMM AQKNLSPSLP GSILQPVQEE NSKTSPRSHR SDGEFSPHSH YSDSDEAS