Recombinant human ATOH1 protein
ATOH1, also known as protein atonal homolog 1, activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. This protein may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. Recombinant human ATOH1 protein was expressed in E. coli.
Product Specifications
Product Name Alternative
Protein atonal homolog 1, ATH1, bHLHa14, HATH1, MATH-1
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
21.3 kDa (198aa)
Additionnal Information
References & Citations
Ben-Arie N., et al. (1996) Hum. Mol. Genet. 5:1207-1216; ; The MGC Project Team (2004) Genome Res. 14:2121-2127
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_005163
Uniprot Accession Number
Q92858
Species
Human
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Urotensin II (UTS2) Human Gene Knockout Kit (CRISPR)
Human Endothelial PAS domain-containing protein 1 (EPAS1) ELISA Kit
Human Endothelial PAS domain-containing protein 1 (EPAS1) ELISA Kit