Recombinant human HOMER2 protein
Homer protein homolog 2, also known as HOMER2, is a member of the homer family of dendritic proteins. Homer family proteins are immediate early gene products that bind to group 1 metabotropic glutamate receptors (mGluRs), proteins involved in triggering intracellular calcium release. HOMER2 have also been shown to link mGluRs with the inositol triphosphate receptors (IP3R) . Recombinant human HOMER2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Homer protein homolog 2, ACPD, CPD, HOMER-2, VESL-2, Cupidin
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
42.1 kDa (368aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Brakeman P R., et al. (1997) Nature. 386:284-288.; ; Tu J C., et al. (1998) Neuron. 21:717-726.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_004830
Uniprot Accession Number
Q9NSB8
Species
Human
AA Sequence
Frequently Asked Questions
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