Recombinant human HOMER2 protein

Homer protein homolog 2, also known as HOMER2, is a member of the homer family of dendritic proteins. Homer family proteins are immediate early gene products that bind to group 1 metabotropic glutamate receptors (mGluRs), proteins involved in triggering intracellular calcium release. HOMER2 have also been shown to link mGluRs with the inositol triphosphate receptors (IP3R) . Recombinant human HOMER2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Homer protein homolog 2, ACPD, CPD, HOMER-2, VESL-2, Cupidin

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

42.1 kDa (368aa) confirmed by MALDI-TOF

Additionnal Information

HOMER2, Homer protein homolog 2, ACPD, CPD, HOMER-2, VESL-2, Cupidin, ATGP1482-10 µg, ATGP1482-20 µg, ATGP1482-50 µg, ATGP1482-100 µg, ATGP1482-250 µg, ATGP1482-500 µg, ATGP1482-1 mg, ATGP1482-10, ATGP1482-20, ATGP1482-50, ATGP1482-100, ATGP1482-250, ATGP1482-500, ATGP1482-1

References & Citations

Brakeman P R., et al. (1997) Nature. 386:284-288.; ; Tu J C., et al. (1998) Neuron. 21:717-726.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_004830

Uniprot Accession Number

Q9NSB8

Species

Human

AA Sequence

MGEQP IFTTRAHVFQ IDPNTKKNWM PASKQAVTVS YFYDVTRNSY RIISVDGAKV IINSTITPNM TFTKTSQKFG QWADSRANTV FGLGFSSEQQ LTKFAEKFQE VKEAAKIAKD KTQEKIETSS NHSQASSVNG TDDEKASHAG PANTHLKSEN DKLKIALTQS AANVKKWEIE LQTLRESNAR LTTALQESAA SVEQWKRQFS ICRDENDRLR NKIDELEEQC SEINREKEKN TQLKRRIEEL EAELREKETE LKDLRKQSEI IPQLMSECEY VSEKLEAAER DNQNLEDKVR SLKTDIEESK YRQRHLKVEL KSFLEVLDGK IDDLHDFRRG LSKLGTDN