What is the catalog number for Recombinant human HIBCH protein?

The catalog number for Recombinant human HIBCH protein is ATGP1469-250.

What sizes are available for Recombinant human HIBCH protein?

Recombinant human HIBCH protein is available in the following size(s): 250 µg.

Is Recombinant human HIBCH protein in stock?

Recombinant human HIBCH protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human HIBCH protein

HIBCH is the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants. Recombinant human HIBCH protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

3-hydroxyisobutyryl-CoA hydrolase mitochondrial, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, HIBYLCOAH

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

42.1 kDa (379aa) confirmed by MALDI-TOF

Additionnal Information

HIBCH, 3-hydroxyisobutyryl-CoA hydrolase mitochondrial, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, HIBYLCOAH, ATGP1469-10 µg, ATGP1469-20 µg, ATGP1469-50 µg, ATGP1469-100 µg, ATGP1469-250 µg, ATGP1469-500 µg, ATGP1469-1 mg, ATGP1469-10, ATGP1469-20, ATGP1469-50, ATGP1469-100, ATGP1469-250, ATGP1469-500, ATGP1469-1

References & Citations

Hendrickson, S.L. et al. (2010) PLoS ONE 5 (9), E12862; ; Wu, C. et al. (2007) Proteomics 7 (11), 1775-1785

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.2M NaCl, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_055177

Uniprot Accession Number

Q6NVY1

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMDAAEE VLLEKKGCTG VITLNRPKFL NALTLNMIRQ IYPQLKKWEQ DPETFLIIIK GAGGKAFCAG GDIRVISEAE KAKQKIAPVF FREEYMLNNA VGSCQKPYVA LIHGITMGGG VGLSVHGQFR VATEKCLFAM PETAIGLFPD VGGGYFLPRL QGKLGYFLAL TGFRLKGRDV YRAGIATHFV DSEKLAMLEE DLLALKSPSK ENIASVLENY HTESKIDRDK SFILEEHMDK INSCFSANTV EEIIENLQQD GSSFALEQLK VINKMSPTSL KITLRQLMEG SSKTLQEVLT MEYRLSQACM RGHDFHEGVR AVLIDKDQSP KWKPADLKEV TEEDLNNHFK SLGSSDLKF