Recombinant human Syndecan-1/SDC1 protein

Syndecan-1 precursor, also known as SDC1, is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. SDC1 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia. Recombinant human SDC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Syndecan-1 precursor, CD138, SDC, SYND1, Syndecan, Syndecan proteoglycan 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

27 kDa (262aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

Syndecan1, CD138, Syndecan-1 precursor, CD138, SDC, SYND1, syndecan, ATGP1467-10 µg, ATGP1467-20 µg, ATGP1467-50 µg, ATGP1467-100 µg, ATGP1467-250 µg, ATGP1467-500 µg, ATGP1467-1 mg, ATGP1467-10, ATGP1467-20, ATGP1467-50, ATGP1467-100, ATGP1467-250, ATGP1467-500, ATGP1467-1

References & Citations

O'Connell FP., et al. (2004) Am J Clin Pathol. 121 (2) :254-63-21531.; ; Rawstron AC., et al. (2006) Curr Protoc Cytom. 6: unit6.23.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_002988.2

Uniprot Accession Number

P18827

Species

Human

AA Sequence

QPALP QIVATNLPPE DQDGSGDDSD NFSGSGAGAL QDITLSQQTP STWKDTQLLT AIPTSPEPTG LEATAASTST LPAGEGPKEG EAVVLPEVEP GLTAREQEAT PRPRETTQLP TTHQASTTTA TTAQEPATSH PHRDMQPGHH ETSTPAGPSQ ADLHTPHTED GGPSATERAA EDGASSQLPA AEGSGEQDFT FETSGENTAV VAVEPDRRNQ SPVDQGATGA SQGLLDRKEV LG