Recombinant human Glutathione S-transferase theta 2/GSTT2 protein

Glutathione S-transferase theta 2, also known as GSTT2, is member of the glutathione s-transferase (GST) family of proteins. There are eight families of GST proteins, namely alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have a variety of functions throughout the cell. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries. Recombinant human GSTT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Glutathione S-transferase theta 2, GSTT2B

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

29.6 kDa (264aa) confirmed by MALDI-TOF

Additionnal Information

GSTT2, Glutathione S-transferase theta 2, GSTT2B, ATGP1464-10 µg, ATGP1464-20 µg, ATGP1464-50 µg, ATGP1464-100 µg, ATGP1464-250 µg, ATGP1464-500 µg, ATGP1464-1 mg, ATGP1464-10, ATGP1464-20, ATGP1464-50, ATGP1464-100, ATGP1464-250, ATGP1464-500, ATGP1464-1

References & Citations

Tan KL., et al. (1995) Genomics. 25 (2) :381-7.; ; Hussey AJ., et al. (1992) Biochem J. 286:929-35.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT

Scientific Category

Metabolism

NCBI Accession Number

NP_000845

Uniprot Accession Number

P0CG29

Species

Human

AA Sequence

MGLELFLDLV SQPSRAVYIF AKKNGIPLEL RTVDLVKGQH KSKEFLQINS LGKLPTLKDG DFILTESSAI LIYLSCKYQT PDHWYPSDLQ ARARVHEYLG WHADCIRGTF GIPLWVQVLG PLIGVQVPEE KVERNRTAMD QALQWLEDKF LGDRPFLAGQ QVTLADLMAL EELMQPVALG YELFEGRPRL AAWRGRVEAF LGAELCQEAH SIILSILEQA AKKTLPTPSP EAYQAMLLRI ARIP