Recombinant human CARD18 protein

Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, uNQ5804

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

12.3 kDa (110aa) confirmed by MALDI-TOF

Additionnal Information

CARD18, Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, uNQ5804, ATGP1460-10 µg, ATGP1460-20 µg, ATGP1460-50 µg, ATGP1460-100 µg, ATGP1460-250 µg, ATGP1460-500 µg, ATGP1460-1 mg, ATGP1460-10, ATGP1460-20, ATGP1460-50, ATGP1460-100, ATGP1460-250, ATGP1460-500, ATGP1460-1