Recombinant human PTPN7 protein

PTPN7, also known as tyrosine-protein phosphatase non-receptor type 7 isoform 1, acts preferentially on tyrosine-phosphorylated MAPK1. This protein plays a role in the regulation of T and B-lymphocyte development and signal transduction. Recombinant human PTPN7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Tyrosine-protein phosphatase non-receptor type 7, Tyrosine-protein phosphatase non-receptor type 7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

43.1 kDa (384aa) confirmed by MALDI-TOF

Additionnal Information

PTPN7, Tyrosine-protein phosphatase non-receptor type 7, Tyrosine-protein phosphatase non-receptor type 7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI, ATGP1453-10 µg, ATGP1453-20 µg, ATGP1453-50 µg, ATGP1453-100 µg, ATGP1453-250 µg, ATGP1453-500 µg, ATGP1453-1 mg, ATGP1453-10, ATGP1453-20, ATGP1453-50, ATGP1453-100, ATGP1453-250, ATGP1453-500, ATGP1453-1

References & Citations

Pettiford S.M., et al. (2000) Oncogene. 19:858-869; ; Nika K., et al. (2004) Biochem. J. 378:335-342;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Scientific Category

Enzymes & Proteases

NCBI Accession Number

NP_002823.2

Uniprot Accession Number

P35236

Species

Human

AA Sequence

MVQAHG GRSRAQPLTL SLGAAMTQPP PEKTPAKKHV RLQERRGSNV ALMLDVRSLG AVEPICSVNT PREVTLHFLR TAGHPLTRWA LQRQPPSPKQ LEEEFLKIPS NFVSPEDLDI PGHASKDRYK TILPNPQSRV CLGRAQSQED GDYINANYIR GYDGKEKVYI ATQGPMPNTV SDFWEMVWQE EVSLIVMLTQ LREGKEKCVH YWPTEEETYG PFQIRIQDMK ECPEYTVRQL TIQYQEERRS VKHILFSAWP DHQTPESAGP LLRLVAEVEE SPETAAHPGP IVVHCSAGIG RTGCFIATRI GCQQLKARGE VDILGIVCQL RLDRGGMIQT AEQYQFLHHT LALYAGQLPE EPSP