Recombinant human Thioredoxin-like 5/TRP14 protein
TXNDC17, also known as thioredoxin domain-containing protein 17, is disulfide reductase. This protein may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. TXNDC17 has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. Recombinant human TXNDC17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Thioredoxin domain-containing protein 17, TRP14, TXNL5
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
16.5 kDa (147aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Jeong W., et al. (2004) J. Biol. Chem. 279:3142-3150; ; Jeong W., et al. (2004) J. Biol. Chem. 279:3151-3159
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.05M NaCl
Scientific Category
Redox Proteins
NCBI Accession Number
NP_116120
Uniprot Accession Number
Q9BRA2
Species
Human
AA Sequence
MARYEE VSVSGFEEFH RAVEQHNGKT IFAYFTGSKD AGGKSWCPDC VQAEPVVREG LKHISEGCVF IYCQVGEKPY WKDPNNDFRK NLKVTAVPTL LKYGTPQKLV ESECLQANLV EMLFSED
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