Recombinant human CMT2/MAD2L1BP protein
MAD2L1-binding protein, also known as MAD2L1BP, belongs to the MAD2L1BP family. This protein may function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. Recombinant human MAD2L1BP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
MAD2L1-binding protein, CMT2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
33.6 kDa (298aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Habu T, et al. (2002) . EMBO J. 21 (23) : 6419-28.; ; Howell BJ, et al. (2000) J Cell Biol. 18; ;150 (6) :1233-50.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 100 mM NaCl
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_055443.1
Uniprot Accession Number
Q15013
Species
Human
AA Sequence
Frequently Asked Questions
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