Recombinant human NXT2 protein

NXT2 (nuclear transport factor 2-like export factor 2) is a member of NXT family proteins that are generally involved in exporting nuclear RNA in eukaryotic cells. This protein is regulator of protein export for NES-containing proteins. Also, it associates with NXF1, NXF2, NXF3 and NXF5 and plays a role in mRNA nuclear export. NXT2 has a critical role in maintaining morphogenetic integrity of embryonic heart in vertebrate species. Recombinant human NXT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

NTF2-related export protein 2, P15-2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

25.3 kDa (221aa) confirmed by MALDI-TOF

Additionnal Information

NXT2, NTF2-related export protein 2, P15-2, ATGP1440-10 µg, ATGP1440-20 µg, ATGP1440-50 µg, ATGP1440-100 µg, ATGP1440-250 µg, ATGP1440-500 µg, ATGP1440-1 mg, ATGP1440-10, ATGP1440-20, ATGP1440-50, ATGP1440-100, ATGP1440-250, ATGP1440-500, ATGP1440-1

References & Citations

Huang H, et al. (2005) BMC Dev Biol. 24;5:7.; ; Herold A, et al. (2000) Mol Cell Biol. 20 (23) :8996-9008.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 40% glycerol, 200 mM NaCl

Scientific Category

Transportation

NCBI Accession Number

NP_061168

Uniprot Accession Number

Q9NPJ8

Species

Human

AA Sequence

HMRKYRS HWSQGDREGY QRRSNYYEGP HTSHSSPADR TREEVVTPTL PEHTATRSQM ATSLDFKTYV DQACRAAEEF VNIYYETMDK RRRALTRLYL DKATLIWNGN AVSGLDALNN FFDTLPSSEF QVNMLDCQPV HEQATQSQTT VLVVTSGTVK FDGNKQHFFN QNFLLTAQST PNNTVWKIAS DCFRFQDWSS S