Recombinant human NXT2 protein
NXT2 (nuclear transport factor 2-like export factor 2) is a member of NXT family proteins that are generally involved in exporting nuclear RNA in eukaryotic cells. This protein is regulator of protein export for NES-containing proteins. Also, it associates with NXF1, NXF2, NXF3 and NXF5 and plays a role in mRNA nuclear export. NXT2 has a critical role in maintaining morphogenetic integrity of embryonic heart in vertebrate species. Recombinant human NXT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
NTF2-related export protein 2, P15-2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
25.3 kDa (221aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Huang H, et al. (2005) BMC Dev Biol. 24;5:7.; ; Herold A, et al. (2000) Mol Cell Biol. 20 (23) :8996-9008.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 40% glycerol, 200 mM NaCl
Scientific Category
Transportation
NCBI Accession Number
NP_061168
Uniprot Accession Number
Q9NPJ8
Species
Human
AA Sequence
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