Recombinant human RRAGC protein
Ras-related GTP binding C, also known as RRAGC, is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways. RRAGC has intrinsic GTPase activity. It also regulates the organization of the actin cytoskeleton. Recombinant human RRAGC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ras-related GTP binding C, GTR2, RAGC
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
46.7 kDa (423aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sekiquchi T., et al. (2001) J Biol Chem. 276:7246-57.; ; Sekiquchi T., et al. (2004) J Biol Chem. 279:8343-50.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_071440
Uniprot Accession Number
Q9HB90
Species
Human
AA Sequence
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