Recombinant human UBL4A protein
UBL4A, also known as GDX, contains 1 ubiquitin-like domain. Post-translational modification by ubiquitin and ubiquitin-related proteins plays critical roles in protein degradation and in regulation of essential cellular processes. In mammals, transcription grinds to a halt during late spermiogenesis due to compaction of the spermatid genome, which creates a special need for robust post-transcriptional regulation. uBL4A plays any role in targeting cellular proteins for degradation. Recombinant human uBL4A protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ubiquitin like 4A, Ubiquitin-like 4, UBL4, Ubiquitin-like protein GDX, DXS254E, GET5, MDY2, TMA24
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
18.8 kDa (165aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Yang F, et al. (2007) Gene Expr Patterns. 7 (1-2) :131-6. ; ; Mariappan M., et al. (2010) Nature 466:1120-1124
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100 mM NaCl
Scientific Category
Ubiquitination
NCBI Accession Number
NP_055050
Uniprot Accession Number
P11441
Species
Human
AA Sequence
Frequently Asked Questions
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