Recombinant human HNRNPA1 protein

HNRNPA1, also known as heterogeneous nuclear ribonucleoprotein A1, involved in the packaging of pre-mRNA into hnRNP particles, transport of poly (A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. This protein may play a role in HCV RNA replication. Recombinant human HNRNPA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Heterogeneous nuclear ribonucleoprotein A1, hnRNP A1, hnRNP-A1, HNRPA1, HNRPA1L3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

36.6 kDa (343aa) confirmed by MALDI-TOF

Additionnal Information

HNRNPA1, Heterogeneous nuclear ribonucleoprotein A1, hnRNP A1, hnRNP-A1, HNRPA1, HNRPA1L3, ATGP1411-10 µg, ATGP1411-20 µg, ATGP1411-50 µg, ATGP1411-100 µg, ATGP1411-250 µg, ATGP1411-500 µg, ATGP1411-1 mg, ATGP1411-10, ATGP1411-20, ATGP1411-50, ATGP1411-100, ATGP1411-250, ATGP1411-500, ATGP1411-1

References & Citations

Kim C.S., et al. (2007) J. Virol. 81:3852-3865; ; Biamonti G., et al. (1989) J. Mol. Biol. 207:491-503

Other References

Nishikawa T, et al. HnRNPA1 interacts with G-quadruplex in the TRA2B promoter and stimulates its transcription in human colon cancer cells. (Sci Rep. 2019) {https://pubmed.ncbi.nlm.nih.gov/31311954/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002127.1

Uniprot Accession Number

P09651

Species

Human

AA Sequence

MSKSESP KEPEQLRKLF IGGLSFETTD ESLRSHFEQW GTLTDCVVMR DPNTKRSRGF GFVTYATVEE VDAAMNARPH KVDGRVVEPK RAVSREDSQR PGAHLTVKKI FVGGIKEDTE EHHLRDYFEQ YGKIEVIEIM TDRGSGKKRG FAFVTFDDHD SVDKIVIQKY HTVNGHNCEV RKALSKQEMA SASSSQRGRS GSGNFGGGRG GGFGGNDNFG RGGNFSGRGG FGGSRGGGGY GGSGDGYNGF GNDGSNFGGG GSYNDFGNYN NQSSNFGPMK GGNFGGRSSG PYGGGGQYFA KPRNQGGYGG SSSSSSYGSG RRF