Recombinant human GMPR protein
GMPR, also known as guanosine monophosphate reductase, catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Recombinant human GMPR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Guanosine monophosphate reductase, GMPR1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
39.5 kDa (365aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Yoshida A., et al. (1990) Cell. 62:11-12; ; Kanno H., et al. (1989) Cell. 58:595-606
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
Scientific Category
Redox Proteins
NCBI Accession Number
AAH08281
Uniprot Accession Number
P36959
Species
Human
AA Sequence
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