Recombinant human ANAPC13 protein
ANAPC13, also known as anaphase-promoting complex subunit 13, is component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. This protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex Recombinant human ANAPC13 protein fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Anaphase-promoting complex subunit 13, APC13, SWM1
Expression System
E.coli
Antigen Species
Human
Tag
T7-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
10 kDa (89aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Schwickart M., et al. (2004) Mol. Cell. Biol. 24:3562-3576; ; Jin L., et al. (2008) Cell. 133:653-665
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 0.1M NaCl
Scientific Category
Ubiquitination
NCBI Accession Number
NP_056206
Uniprot Accession Number
Q9BS18
Species
Human
AA Sequence
MASMTGGQQM GRGSHMDSEV QRDGRILDLI DDAWREDKLP YEDVAIPLNE LPEPEQDNGG TTESVKEQEM KWTDLALQYL HENVPPIGN
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
NUMA1 (Nuclear Mitotic Apparatus Protein 1, NuMA Protein, SP-H Antigen, NUMA) (MaxLight 550)
NUMA1 (Nuclear Mitotic Apparatus Protein 1, NuMA Protein, SP-H Antigen, NUMA) (MaxLight 550)
Hepatitis B Surface Antigen IgG Antibody ELISA Kit, Monkey
APC/iFluor® 750 Anti-human CD268 Antibody *11C1*