Recombinant human GIPC2 protein

GIPC2, also known as, SEMCAP2 contains 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. GIPC2 is expressed at high levels in kidney and colon and at lower levels in adult liver. It might play important roles in human gastric cancer through modulation of growth factor signaling or cell adhesion. Recombinant human GIPC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

PDZ domain containing family member 2, PDZ domain containing family, member 2, SEMCAP2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

36.9 kDa (339aa) confirmed by MALDI-TOF

Additionnal Information

GIPC2, PDZ domain containing family member 2, PDZ domain containing family, member 2, SEMCAP2, ATGP1400-10 µg, ATGP1400-20 µg, ATGP1400-50 µg, ATGP1400-100 µg, ATGP1400-250 µg, ATGP1400-500 µg, ATGP1400-1 mg, ATGP1400-10, ATGP1400-20, ATGP1400-50, ATGP1400-100, ATGP1400-250, ATGP1400-500, ATGP1400-1

References & Citations

Katoh M., et al. (2002) J Mol Med. 9:585-589.; ; Kirikoshi H., et al. (2002) J Oncol. 20:1183-1187.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

AAH36075

Uniprot Accession Number

Q8TF65

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMPLKLR GKKKAKSKET AGLVEGEPTG AGGGSLSASR APARRLVFHA QLAHGSATGR VEGFSSIQEL YAQIAGAFEI SPSEILYCTL NTPKIDMERL LGGQLGLEDF IFAHVKGIEK EVNVYKSEDS LGLTITDNGV GYAFIKRIKD GGVIDSVKTI CVGDHIESIN GENIVGWRHY DVAKKLKELK KEELFTMKLI EPKKAFEIEP RSKAGKSSGE KIGCGRATLR LRSKGPATVE EMPSETKAKA IEKIDDVLEL YMGIRDIDLA TTMFEAGKDK VNPDEFAVAL DETLGDFAFP DEFVFDVWGV IGDAKRRGL