Recombinant human YEATS4 protein

YEATS4 has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Recombinant human YEATS4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

YEATS domain-containing protein 4, 4930573H17Rik, B230215M10Rik, GAS41, NuBI-1, YAF9, YEATS domain containing 4, Glioma-amplified sequence 41

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

28.9 kDa (250aa) confirmed by MALDI-TOF

Additionnal Information

YEATS4, YEATS domain-containing protein 4, 4930573H17Rik, B230215M10Rik, GAS41, NuBI-1, YAF9, YEATS domain containing 4, Glioma-amplified sequence 41, ATGP1365-10 µg, ATGP1365-20 µg, ATGP1365-50 µg, ATGP1365-100 µg, ATGP1365-250 µg, ATGP1365-500 µg, ATGP1365-1 mg, ATGP1365-10, ATGP1365-20, ATGP1365-50, ATGP1365-100, ATGP1365-250, ATGP1365-500, ATGP1365-1

References & Citations

Harborth J. et al. (2000) J. Biol. Chem. 275:31979-31985.; ; Debernardi S. et al. (2002) Blood. 99: 275-81.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 50% glycerol, 2mM DTT, 0.2M NaCl, 0.1mM PMSF, 50 mM Imidazole

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_006521

Uniprot Accession Number

O95619

Species

Human

AA Sequence

MFKRMAE FGPDSGGRVK GVTIVKPIVY GNVARYFGKK REEDGHTHQW TVYVKPYRNE DMSAYVKKIQ FKLHESYGNP LRVVTKPPYE ITETGWGEFE IIIKIFFIDP NERPVTLYHL LKLFQSDTNA MLGKKTVVSE FYDEMIFQDP TAMMQQLLTT SRQLTLGAYK HETEFAELEV KTREKLEAAK KKTSFEIAEL KERLKASRET INCLKNEIRK LEEDDQAKDI