Recombinant human YEATS4 protein
YEATS4 has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Recombinant human YEATS4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
YEATS domain-containing protein 4, 4930573H17Rik, B230215M10Rik, GAS41, NuBI-1, YAF9, YEATS domain containing 4, Glioma-amplified sequence 41
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
28.9 kDa (250aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Harborth J. et al. (2000) J. Biol. Chem. 275:31979-31985.; ; Debernardi S. et al. (2002) Blood. 99: 275-81.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 50% glycerol, 2mM DTT, 0.2M NaCl, 0.1mM PMSF, 50 mM Imidazole
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_006521
Uniprot Accession Number
O95619
Species
Human
AA Sequence
Frequently Asked Questions
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