Recombinant human SNTA1 protein

SNTA1 is a member of the syntrophin gene family, which is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. Recombinant human SNTA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Syntrophin alpha 1, Syntrophin, alpha 1, dJ1187J4.5, LQT12, SNT1, TACIP1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

56.3 kDa (528aa) confirmed by MALDI-TOF

Additionnal Information

SNTA1, Syntrophin alpha 1, Syntrophin, alpha 1, dJ1187J4.5, LQT12, SNT1, TACIP1, ATGP1362-10 µg, ATGP1362-20 µg, ATGP1362-50 µg, ATGP1362-100 µg, ATGP1362-250 µg, ATGP1362-500 µg, ATGP1362-1 mg, ATGP1362-10, ATGP1362-20, ATGP1362-50, ATGP1362-100, ATGP1362-250, ATGP1362-500, ATGP1362-1

References & Citations

Newey SE., et al. (2000) Curr Biol. 10 (20) :1295-8.; ; Adams ME., et al. (2000) J Cell Biol. 150 (6) :1385-98.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_003089.1

Uniprot Accession Number

Q13424

Species

Human

AA Sequence

MASGRRA PRTGLLELRA GAGSGAGGER WQRVLLSLAE DVLTVSPADG DPGPEPGAPR EQEPAQLNGA AEPGAGPPQL PEALLLQRRR VTVRKADAGG LGISIKGGRE NKMPILISKI FKGLAADQTE ALFVGDAILS VNGEDLSSAT HDEAVQVLKK TGKEVVLEVK YMKDVSPYFK NSTGGTSVGW DSPPASPLQR QPSSPGPTPR NFSEAKHMSL KMAYVSKRCT PNDPEPRYLE ICSADGQDTL FLRAKDEASA RSWATAIQAQ VNTLTPRVKD ELQALLAATS TAGSQDIKQI GWLTEQLPSG GTAPTLALLT EKELLLYLSL PETREALSRP ARTAPLIATR LVHSGPSKGS VPYDAELSFA LRTGTRHGVD THLFSVESPQ ELAAWTRQLV DGCHRAAEGV QEVSTACTWN GRPCSLSVHI DKGFTLWAAE PGAARAVLLR QPFEKLQMSS DDGASLLFLD FGGAEGEIQL DLHSCPKTIV FIIHSFLSAK VTRLGLLA