Recombinant human RTN4IP1 protein
RTN4IP1 is a novel mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. The interaction of reticulon 4 with mitochondrial proteins may provide insight into the mechanisms for reticulon-induced inhibition of neurite growth. Recombinant human RTN4IP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Reticulon-4-interacting protein 1, MGC12934, NIMP, Reticulon 4 interacting protein 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
41.4 kDa (379aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Huber A.B. et al. (2000) Biol. Chem. 381: 407-419.; ; Hu W.H. et al. (2002) J. Neurochem. 81: 36-45.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
Scientific Category
Metabolism
NCBI Accession Number
NP_116119
Uniprot Accession Number
Q8WWV3
Species
Human
AA Sequence
Frequently Asked Questions
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