Recombinant human G3BP2 protein

G3BP2, also known as ras GTPase-activating protein-binding protein 2, is localized to the plasma membrane and endocytic compartments and controls a fast endocytic recycling pathway. This protein probably is scaffold protein that may be involved in mRNA transport. Recombinant human G3BP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Ras GTPase-activating protein-binding protein 2, G3BP-2, GAP SH3 domain-binding protein 2, KIAA0660, GTPase activating protein (SH3 domain) binding protein 2, G3BP stress granule assembly factor 2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

53.3 kDa (473aa)

Additionnal Information

G3BP2, Ras GTPase-activating protein-binding protein 2, G3BP-2, GAP SH3 domain-binding protein 2, KIAA0660, GTPase activating protein (SH3 domain) binding protein 2, ATGP1344-10 µg, ATGP1344-20 µg, ATGP1344-50 µg, ATGP1344-100 µg, ATGP1344-250 µg, ATGP1344-500 µg, ATGP1344-1 mg, ATGP1344-10, ATGP1344-20, ATGP1344-50, ATGP1344-100, ATGP1344-250, ATGP1344-500, ATGP1344-1

References & Citations

Prigent M., et al. (2000) J Biol Chem. 275: 36441-36449.; ; Wu C. et al. (2007) Proteomics 7: 1775-1785.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.2M NaCl,2mM DTT, 0.1mM PMSF

Scientific Category

Signal Transduction

NCBI Accession Number

NP_987100.1

Uniprot Accession Number

Q9UN86

Species

Human

AA Sequence

MVMEKP SPLLVGREFV RQYYTLLNKA PEYLHRFYGR NSSYVHGGVD ASGKPQEAVY GQNDIHHKVL SLNFSECHTK IRHVDAHATL SDGVVVQVMG LLSNSGQPER KFMQTFVLAP EGSVPNKFYV HNDMFRYEDE VFGDSEPELD EESEDEVEEE QEERQPSPEP VQENANSGYY EAHPVTNGIE EPLEESSHEP EPEPESETKT EELKPQVEEK NLEELEEKST TPPPAEPVSL PQEPPKPRVE AKPEVQSQPP RVREQRPRER PGFPPRGPRP GRGDMEQNDS DNRRIIRYPD SHQLFVGNLP HDIDENELKE FFMSFGNVVE LRINTKGVGG KLPNFGFVVF DDSEPVQRIL IAKPIMFRGE VRLNVEEKKT RAARERETRG GGDDRRDIRR NDRGPGGPRG IVGGGMMRDR DGRGPPPRGG MAQKLGSGRG TGQMEGRFTG QRR