Recombinant human CCNG1 protein

CCNG1, also known as cyclin-G1, is a member of the cyclin family and contains the cyclin box. It may play a role in growth regulation and be associated with G2/M phase arrest in response to DNA damage. It may be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. Recombinant human CCNG1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Cyclin-G1, CCNG, CYCG1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

36.2 kDa (315aa) confirmed by MALDI-TOF

Additionnal Information

CCNG1, Cyclin-G1, CCNG, CYCG1, ATGP1331-10 µg, ATGP1331-20 µg, ATGP1331-50 µg, ATGP1331-100 µg, ATGP1331-250 µg, ATGP1331-500 µg, ATGP1331-1 mg, ATGP1331-10, ATGP1331-20, ATGP1331-50, ATGP1331-100, ATGP1331-250, ATGP1331-500, ATGP1331-1

References & Citations

Horne M.C., et al. (1996) J. Biol. Chem. 271:6050-6061; ; Bates S.A., et al. (1996) Oncogene. 13:1103-1109

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaCl, 5mM DTT

Scientific Category

Cell Cycle

NCBI Accession Number

NP_954854.1

Uniprot Accession Number

P51959

Species

Human

AA Sequence

MIEVLTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS CFYLAVKSIE EERNVPLATD LIRISQYRFT VSDLMRMEKI VLEKVCWKVK ATTAFQFLQL YYSLLQENLP LERRNSINFE RLEAQLKACH CRIIFSKAKP SVLALSIIAL EIQAQKCVEL TEGIECLQKH SKINGRDLTF WQELVSKCLT EYSSNKCSKP NVQKLKWIVS GRTARQLKHS YYRITHLPTI PEMVP