Recombinant human CCNG1 protein
CCNG1, also known as cyclin-G1, is a member of the cyclin family and contains the cyclin box. It may play a role in growth regulation and be associated with G2/M phase arrest in response to DNA damage. It may be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. Recombinant human CCNG1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Cyclin-G1, CCNG, CYCG1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
36.2 kDa (315aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Horne M.C., et al. (1996) J. Biol. Chem. 271:6050-6061; ; Bates S.A., et al. (1996) Oncogene. 13:1103-1109
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaCl, 5mM DTT
Scientific Category
Cell Cycle
NCBI Accession Number
NP_954854.1
Uniprot Accession Number
P51959
Species
Human
AA Sequence
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