Recombinant human RBBP9 protein

Retinoblastoma binding protein, also known as RBBP9, localizes to both the nucleus and the cytoplasm. RBBP9 is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Specifically, RBBP9 interacts with retinoblastoma (Rb) and provides cellular resistance to the growth-inhibitory effects of TGFbeta1, thus facilitating the cellular transformation process. Recombinant human RBBP9 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Retinoblastoma binding protein 9, BOG, RBBP10

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

23.1 kDa (206aa) confirmed by MALDI-TOF

Additionnal Information

RBBP9, Retinoblastoma binding protein 9, BOG, RBBP10, ATGP1311-10 µg, ATGP1311-20 µg, ATGP1311-50 µg, ATGP1311-100 µg, ATGP1311-250 µg, ATGP1311-500 µg, ATGP1311-1 mg, ATGP1311-10, ATGP1311-20, ATGP1311-50, ATGP1311-100, ATGP1311-250, ATGP1311-500, ATGP1311-1

References & Citations

Woitach J T., et al. (1998) Nat Genet. 19:371-374.; ; Woitach J T., et al. (1999) Cytogenet Cell Genet. 85:252-253.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_006597

Uniprot Accession Number

O75884

Species

Human

AA Sequence

MASPSKAVIV PGNGGGDVTT HGWYGWVKKE LEKIPGFQCL AKNMPDPITA RESIWLPFME TELHCDEKTI IIGHSSGAIA AMRYAETHRV YAIVLVSAYT SDLGDENERA SGYFTRPWQW EKIKANCPYI VQFGSTDDPF LPWKEQQEVA DRLETKLHKF TDCGHFQNTE FHELITVVKS LLKVPA