Recombinant human Retinol Binding Protein 1/RBP1 protein
RBP1 (Retinol binding protein 1) belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. RBP1 can also act as a bridging molecule to recruit histone deacetylases (HDACs), proteins that function as potent regulators of gene expression. This protein is detected in nearly all the tissues with higher expression in adult ovary, pancreas, pituitary gland and adrenal gland, and fetal liver. Recombinant human RBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Retinol binding protein 1, RBPC, CRABP-I, CRBPI, CRBP, CRBP1, Cellular retinol binding protein 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.7 kDa (220aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Lai, A., et al. (2001) Mol. Cell. Biol. 21: 2918-2932.; ; Folli C., et al. (2001) Proc. Natl. Acad. Sci. u.S.A. 98:3710-3715
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200 mM NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_002890
Uniprot Accession Number
P09455
Species
Human
AA Sequence
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