Recombinant human Retinol Binding Protein 1/RBP1 protein

RBP1 (Retinol binding protein 1) belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. RBP1 can also act as a bridging molecule to recruit histone deacetylases (HDACs), proteins that function as potent regulators of gene expression. This protein is detected in nearly all the tissues with higher expression in adult ovary, pancreas, pituitary gland and adrenal gland, and fetal liver. Recombinant human RBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Retinol binding protein 1, RBPC, CRABP-I, CRBPI, CRBP, CRBP1, Cellular retinol binding protein 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.7 kDa (220aa) confirmed by MALDI-TOF

Additionnal Information

RBP1, retinol binding protein 1, CRABP-I, CRBP, CRBP1, CRBPI, RBPC, ATGP1303-10 µg, ATGP1303-20 µg, ATGP1303-50 µg, ATGP1303-100 µg, ATGP1303-250 µg, ATGP1303-500 µg, ATGP1303-1 mg, ATGP1303-10, ATGP1303-20, ATGP1303-50, ATGP1303-100, ATGP1303-250, ATGP1303-500, ATGP1303-1

References & Citations

Lai, A., et al. (2001) Mol. Cell. Biol. 21: 2918-2932.; ; Folli C., et al. (2001) Proc. Natl. Acad. Sci. u.S.A. 98:3710-3715

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200 mM NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002890

Uniprot Accession Number

P09455

Species

Human

AA Sequence

MDPPAGF VRAGNPAVAA PQSPLSPEGA HFRAAHHPRS TGSRCPGSLQ PSRPLVANWL QSLPEMPVDF TGYWKMLVNE NFEEYLRALD VNVALRKIAN LLKPDKEIVQ DGDHMIIRTL STFRNYIMDF QVGKEFEEDL TGIDDRKCMT TVSWDGDKLQ CVQKGEKEGR GWTQWIEGDE LHLEMRVEGV VCKQVFKKVQ