Recombinant human I-TAC/CXCL11 protein

Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9) . CXCL11 is strongly induced by IFN-gamma and IFN-beta, and weakly induced by IFN-alpha. It is chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. Recombinant human CXCL11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Product Specifications

Product Name Alternative

C-X-C motif chemokine ligand 11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, SCYB11, SCYB9B, b-R1, IP-9

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 85% by SDS-PAGE

Molecular Weight

10.6 kDa (94aa) confirmed by MALDI-TOF

Additionnal Information

CXCL11, I-TAC, C-X-C motif chemokine 11, b-R1, H174, I-TAC, IP-9, IP9, MGC102770, SCYB11, SCYB9B, ATGP1296-10 µg, ATGP1296-20 µg, ATGP1296-50 µg, ATGP1296-100 µg, ATGP1296-250 µg, ATGP1296-500 µg, ATGP1296-1 mg, ATGP1296-10, ATGP1296-20, ATGP1296-50, ATGP1296-100, ATGP1296-250, ATGP1296-500, ATGP1296-1