Recombinant human RAB34 protein
RAB34, also known as ras-related protein Rab34, is localized to the plasma membrane and endocytic compartments and controls a fast endocytic recycling pathway. This protein is involved in protein transport, specifically the redistribution of lysosomes to the peri-Golgi region. In fibroblasts, this protein was colocalized with actin to the membrane ruffles and membranes of relatively large vesicles adjacent to the ruffles. Recombinant human RAB34 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
31.2 kDa (279aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sun P. et al. (2003) J Biol Chem. 278 :4063-71.; ; Novick P. et al. (1993) Cell. 75: 597-601.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.1M NaCl,1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_114140
Uniprot Accession Number
Q9BZG1
Species
Human
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Piperazine-1,4- Bis (2 -EthaneSulphonic Acid) (Pipes Buffer) 99.0% Plant Culture Tested