Recombinant human RAB18 protein

RAB18 is a member of a family of Ras-related small GTPase that is lipid-anchored to the cytoplasmic side of the cell membrane. It plays a role in apical recycling and endocytosis and is also thought to be involved in protein transport between early endosomes and the plasma membrane. Recombinant human Rab18 protein, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ras-related protein Rab-18, RAB18LI1, RAB18 member RAS oncogene family

Expression System

E.coli

Antigen Species

Human

Tag

T7-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.5 kDa (221aa)

Additionnal Information

RAB18, Ras-related protein Rab-18, RAB18LI1, ATGP1289-10 µg, ATGP1289-20 µg, ATGP1289-50 µg, ATGP1289-100 µg, ATGP1289-250 µg, ATGP1289-500 µg, ATGP1289-1 mg, ATGP1289-10, ATGP1289-20, ATGP1289-50, ATGP1289-100, ATGP1289-250, ATGP1289-500, ATGP1289-1

References & Citations

McMurtrie EB., et al. (1997) Genomics. 45 (3) :623-5.; ; Ozeki S., et al. (2005) J Cell Sci. 118 (12) :2601-11.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_067075.1

Uniprot Accession Number

Q9NP72

Species

Human

AA Sequence

MDEDV LTTLKILIIG ESGVGKSSLL LRFTDDTFDP ELAATIGVDF KVKTISVDGN KAKLAIWDTA GQERFRTLTP SYYRGAQGVI LVYDVTRRDT FVKLDNWLNE LETYCTRNDI VNMLVGNKID KENREVDRNE GLKFARKHSM LFIEASAKTC DGVQCAFEEL VEKIIQTPGL WESENQNKGV KLSHREEGQG GGACGGYCSV L