Recombinant human RAB18 protein
RAB18 is a member of a family of Ras-related small GTPase that is lipid-anchored to the cytoplasmic side of the cell membrane. It plays a role in apical recycling and endocytosis and is also thought to be involved in protein transport between early endosomes and the plasma membrane. Recombinant human Rab18 protein, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ras-related protein Rab-18, RAB18LI1, RAB18 member RAS oncogene family
Expression System
E.coli
Antigen Species
Human
Tag
T7-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.5 kDa (221aa)
Additionnal Information
References & Citations
McMurtrie EB., et al. (1997) Genomics. 45 (3) :623-5.; ; Ozeki S., et al. (2005) J Cell Sci. 118 (12) :2601-11.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_067075.1
Uniprot Accession Number
Q9NP72
Species
Human
AA Sequence
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