Recombinant human ACADL protein

ACADL belongs to the acyl-CoA dehydrogenase family, existing as a homotetramer. It is involved in the catabolism of fatty acids and amino acids and they provide a major source of energy for the heart and skeletal muscle. Defect in the gene encoding ACADL leads to non-ketotic hypoglycemia and hypotonia, muscle weakness. Recombinant human ACADL protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Acyl-CoA dehydrogenase long chain, Acyl-CoA dehydrogenase, long chain, ACAD4, FLJ94052, LCAD

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

46.7 kDa (421aa) confirmed by MALDI-TOF

Additionnal Information

ACADL, Acyl-CoA dehydrogenase long chain, Acyl-CoA dehydrogenase, long chain, ACAD4, FLJ94052, LCAD, ATGP1278-10 µg, ATGP1278-20 µg, ATGP1278-50 µg, ATGP1278-100 µg, ATGP1278-250 µg, ATGP1278-500 µg, ATGP1278-1 mg, ATGP1278-10, ATGP1278-20, ATGP1278-50, ATGP1278-100, ATGP1278-250, ATGP1278-500, ATGP1278-1

References & Citations

Maher AC., et al. (2010) Mol Genet Metab. 100 (2) :163-7.; ; Wanders RJ., et al. (1998) Biochim Biophys Acta. 1393 (1) :35-40.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl

Scientific Category

Cancer

NCBI Accession Number

NP_001599

Uniprot Accession Number

P28330

Species

Human

AA Sequence

GGEERLETP SAKKLTDIGI RRIFSPEHDI FRKSVRKFFQ EEVIPHHSEW EKAGEVSREV WEKAGKQGLL GVNIAEHLGG IGGDLYSAAI VWEEQAYSNC SGPGFSIHSG IVMSYITNHG SEEQIKHFIP QMTAGKCIGA IAMTEPGAGS DLQGIKTNAK KDGSDWILNG SKVFISNGSL SDVVIVVAVT NHEAPSPAHG ISLFLVENGM KGFIKGRKLH KMGLKAQDTA ELFFEDIRLP ASALLGEENK GFYYIMKELP QERLLIADVA ISASEFMFEE TRNYVKQRKA FGKTVAHLQT VQHKLAELKT HICVTRAFVD NCLQLHEAKR LDSATACMAK YWASELQNSV AYDCVQLHGG WGYMWEYPIA KAYVDARVQP IYGGTNEIMK ELIAREIVFD K