Recombinant human alpha 1-Microglobulin protein
Alpha-1-microglobulin, also known as AMBP, is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function. AMBP specifically interacts with the ORF3 protein of hepatitis E virus and has a direct role in enhancing alpha-1 microglobulin export from the hepatocyte. Recombinant human AMBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Protein AMBP, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, uTI
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.1 kDa (205aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Vetr H., et al. (1990) Bio Chem Hoppe Seyler. 371:1185-1196.; ; Sala A., et al. (2004) J Biol Chem. 279:51033-51041.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_001624.1
Uniprot Accession Number
P02760
Species
Human
AA Sequence
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