Recombinant human alpha 1-Microglobulin protein

Alpha-1-microglobulin, also known as AMBP, is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function. AMBP specifically interacts with the ORF3 protein of hepatitis E virus and has a direct role in enhancing alpha-1 microglobulin export from the hepatocyte. Recombinant human AMBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Protein AMBP, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, uTI

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

23.1 kDa (205aa) confirmed by MALDI-TOF

Additionnal Information

A1-Microglobulin, Protein AMBP, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, uTI, ATGP1258-10 µg, ATGP1258-20 µg, ATGP1258-50 µg, ATGP1258-100 µg, ATGP1258-250 µg, ATGP1258-500 µg, ATGP1258-1 mg, ATGP1258-10, ATGP1258-20, ATGP1258-50, ATGP1258-100, ATGP1258-250, ATGP1258-500, ATGP1258-1

References & Citations

Vetr H., et al. (1990) Bio Chem Hoppe Seyler. 371:1185-1196.; ; Sala A., et al. (2004) J Biol Chem. 279:51033-51041.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Scientific Category

Cancer

NCBI Accession Number

NP_001624.1

Uniprot Accession Number

P02760

Species

Human

AA Sequence

GPVPTPPDN IQVQENFNIS RIYGKWYNLA IGSTCPWLKK IMDRMTVSTL VLGEGATEAE ISMTSTRWRK GVCEETSGAY EKTDTDGKFL YHKSKWNITM ESYVVHTNYD EYAIFLTKKF SRHHGPTITA KLYGRAPQLR ETLLQDFRVV AQGVGIPEDS IFTMADRGEC VPGEQEPEPI LIPRV