Recombinant human GITR Ligand/TNFSF18 protein

TNFSF18, also known as GITRL, belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It is Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 protein was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Product Specifications

Product Name Alternative

Activation-inducible TNF-related ligand, AITRL, GITRL, Glucocorticoid-induced TNF-related ligand, hGITRL, TL6, TNF superfamily member 18, Tumor necrosis factor (ligand) superfamily member 18

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

14.6 kDa (129aa) confirmed by MALDI-TOF

Additionnal Information

GITR Ligand, TNFSF18, Tumor necrosis factor (ligand) superfamily member 18, AITRL, TL6, GITRL, hGITRL, ATGP1249-10 µg, ATGP1249-20 µg, ATGP1249-50 µg, ATGP1249-100 µg, ATGP1249-250 µg, ATGP1249-500 µg, ATGP1249-1 mg, ATGP1249-10, ATGP1249-20, ATGP1249-50, ATGP1249-100, ATGP1249-250, ATGP1249-500, ATGP1249-1