Recombinant human Angiopoietin 1/ANGPT1 protein

Human ANGPT1 is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. This protein is glycosylated and has a fibrinogen-like domain at the carboxy terminus and coiled-coil regions in the amino terminus. ANGPT1 is an angiogenic factor that mediates blood vessel maturation and may be involved in endothelial development. Recombinant human ANGPT1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Angiopoietin 1, AGP1, AGPT, ANG1

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

55.6 kDa (480aa)

Additionnal Information

Angiopoietin1, Angiopoietin 1, AGP1, AGPT, ANG1, ATGP1236-10 µg, ATGP1236-20 µg, ATGP1236-50 µg, ATGP1236-100 µg, ATGP1236-250 µg, ATGP1236-500 µg, ATGP1236-1 mg, ATGP1236-10, ATGP1236-20, ATGP1236-50, ATGP1236-100, ATGP1236-250, ATGP1236-500, ATGP1236-1

References & Citations

Kopczynska E., et al. (2009) Eur J Gynaecol Oncol. 30 (6) :646-9.; ; Davis S., et al. (1996) Cell. 87 (7) :1161-9.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) 1M urea, 5% glycerol

Scientific Category

Apoptosis

NCBI Accession Number

NP_001137

Uniprot Accession Number

Q15389

Species

Human

AA Sequence

MSNQRRSPEN SGRRYNRIQH GQCAYTFILP EHDGNCREST TDQYNTNALQ RDAPHVEPDF SSQKLQHLEH VMENYTQWLQ KLENYIVENM KSEMAQIQQN AVQNHTATML EIGTSLLSQT AEQTRKLTDV ETQVLNQTSR LEIQLLENSL STYKLEKQLL QQTNEILKIH EKNSLLEHKI LEMEGKHKEE LDTLKEEKEN LQGLVTRQTY IIQELEKQLN RATTNNSVLQ KQQLELMDTV HNLVNLCTKE GVLLKGGKRE EEKPFRDCAD VYQAGFNKSG IYTIYINNMP EPKKVFCNMD VNGGGWTVIQ HREDGSLDFQ RGWKEYKMGF GNPSGEYWLG NEFIFAITSQ RQYMLRIELM DWEGNRAYSQ YDRFHIGNEK QNYRLYLKGH TGTAGKQSSL ILHGADFSTK DADNDNCMCK CALMLTGGWW FDACGPSNLN GMFYTAGQNH GKLNGIKWHY FKGPSYSLRS TTMMIRPLDF