Recombinant human Transgelin 3/TAGLN3 protein
TAGLN3, also known as transgelin-3, contains a putative Actin-binding domain, two EF-hand motifs, two potential phosphorylation sites and a calponin-homology (CH) domain. It shares homology with transgelin and calponin, two cytoskeleton-interacting proteins. Belonging to the calponin family, TAGLN3 co-localizes with Actin and tubulin, suggesting a possible role for it in neuronal plasticity or as a signaling protein. Due to a varied expression pattern, it may play different roles in the developing and adult brain. Recombinant human TAGLN3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Transgelin-3, NP22, NP25
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.6 kDa (219aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Ren W.Z. et al. (1994) Brain Res.Mol. Brain Res. 22: 173-185.; ; Fan L. et al. (2001) J. Neurochem. 76: 1275-1281.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Scientific Category
Neuroscience
NCBI Accession Number
NP_037391.2
Uniprot Accession Number
Q9UI15
Species
Human
AA Sequence
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