(S) -Mephenytoin (Standard)

(S) -Mephenytoin (Standard) is the analytical standard of (S) -Mephenytoin. This product is intended for research and analytical applications. (S) -Mephenytoin ((+) -Mephenytoin) is an anticonvulsive agent. (S) -Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S) -Mephenytoin can be used for the analysis of cytochrome P450 metabolism[1][2].

Product Specifications

CAS Number

[70989-04-7]

Product Name Alternative

(+) -Mephenytoin (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-mephenytoin-standard.html

Purity

99.93

Smiles

O=C1N(C)C([C@@](C2=CC=CC=C2)(CC)N1)=O

Molecular Formula

C12H14N2O2

Molecular Weight

218.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Shimada T, et, al. Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction. J Biol Chem. 1986 Jan 15;261 (2) :909-21.|[2]Goldstein JA, et, al. Evidence that CYP2C19 is the major (S) -mephenytoin 4'-hydroxylase in humans. Biochemistry. 1994 Feb 22;33 (7) :1743-52.